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Home > Cordless-Microscopes News > Chromosomal Laboratories Appoints R. Vincent Miller, Ph.D., Vice President And Chief Technical Officer

Chromosomal Laboratories Appoints R. Vincent Miller, Ph.D., Vice President And Chief Technical Officer




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Development and Application of an Internet Electron Microscopy System for the Outreach Program in Japan
Research Articles
Miyoko Tanaka, Akane Tameike, Nobuhiro Ishikawa, Kazuo Furuya,
Microscopy and Microanalysis, Volume 14 Issue 02 , pp 176-183

Abstract
The development of a remotely operated scanning electron microscopy (SEM) system and its use by high school students and the public as an outreach program are reported. The SEM and the server are located in the National Institute for Materials Science, Tsukuba, Japan, with client computers installed at a science museum and high schools. Using a secure virtual private network system and scheduling management groupware, observation of SEM images and energy dispersive X-ray analysis are widely and frequently performed throughout Japan.
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Personality and Colorectal Cancer: The Fukuoka Colorectal Cancer Study
Objective

Although personality factors, especially emotional suppression and loss-hopelessness, have been linked to the occurrence and progression of cancer, little is reported specifically on colorectal cancer. It has also been claimed that a ‘hysterical’ personality characterized by exaggerated emotional expressions, egocentricity and ambivalent connection may be protective from cancer. This community-based case–control study examined whether personality factors relevant to emotional suppression or loss-hopelessness are associated with an increased risk of colorectal cancer, and whether factors related to the hysterical personality are associated with a decreased risk.

Methods

The stress inventory (SI), a self-administered questionnaire to assess the possible disease-prone and other relevant personalities in Japanese, was completed by 497 patients with newly diagnosed colorectal cancer and 809 controls randomly selected in the Fukuoka area of Japan.

Results

After controlling for age, sex and residence using a logistic regression model, none of the SI scales relevant to emotional suppression (‘unfulfilled needs for acceptance’, ‘altruism’, ‘rationalizing conflicts/frustrations’) or loss-hopelessness (‘low sense of control’, ‘object-dependence/loss’, ‘object-dependence/happiness’) was related to colorectal cancer. On the other hand, two scales representing elements of the hysterical personality, ‘object-dependence/ambivalence’ and ‘egoism’ were protectively associated with risk. Additional adjustment for body-mass index and lifestyle factors did not materially change these associations.

Conclusions

Although personalities relevant to the emotional suppression or loss-hopelessness may not be a risk factor for colorectal cancer in the Japanese population, ambivalent connection and egocentricity may be protective.

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Science 2.0 - a new way of doing research?
Web 2.0 as a platform has begun to transform the web and already divides users into first generation and second generation internet users. Certainly in the online travel arena, which I know well, for many younger people, there is increasing evidence that email and static web content is no longer being used, with dynamic content, interactive websites, chat forums and instant messaging the norm for this second generation - in particular social networking is becoming the dominant form of web traffic through the popularity of review sites for travel and purchasing like Tripadvisor, social networking sites like Facebook and Bebo and social contribution sites like wikipedia.

There is now a move online to take science research into the social networking category also, with research publications being released into the wild for instant review in the form of online commentary from the science community rather than peer review prior to publication as happens most often now. Science 2.0 could bring information on stream much more quickly, but of course does so with a caveat that the work has yet to be tested. A project that began in MIT is set to go more mainstream - OpenNetWare in the biological sciences. The approach is likely to proliferate among younger scientists in the coming years. Scientific American discusses whether this will be a good thing or a bad thing for science.

See Scientific American.
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Encyclopedia of Life is Online
The Encyclopedia of Life, intended to become an online catalog of all species on Earth, began its alpha test of 30,000 pages yesterday. There are placeholders for 1 million species. (FYI, there are estimated to be 1.8 million known species on Earth, and of course more that have yet to be identified.)

This project is notable not just on its face as a remarkable collection of information, contributed by top scientists. It is also remarkable because it opens vast new amounts of information to everyone in an easily accessed way. It also shows the power of collaboration. This is not exactly citizen science, since the contributions will come from experts. However, it will take a large community of experts to make the Encyclopedia a reality. As the site grows, it should give readers a view of the inner workings of science, since there will certainly be disagreements about what species goes where, what the implications of certain connections are, etc. E.O. Wilson, the eminent Harvard biologist who inspired the site and has led its development, observes, "This great effort promises to lay out new directions for research in every branch of biology."

By making this valuable information accessible to everyone, the EOL project should inspire many years of learning opportunities at all levels.

Link to Encyclopedia of Life
Link to Tree of Life (A related site that is also great)
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Carpal Tunnel Syndrome: A Case-Control Study Evaluating Its Relationship with Body Mass Index and Hand and Wrist Measurements

This case–control study investigated the associations between the body mass index (BMI), hand and wrist measurements and carpal tunnel syndrome (CTS). The hands and wrists of 50 patients with CTS and 50 age- and sex-matched controls were measured. The right and left wrist indices (wrist depth/wrist width) were significantly greater in CTS patients (mean = 0.71. SD = 0.04) than in the controls (mean = 0.69 SD = 0.04). The hand index (hand length/palm width) and BMI were not significantly different in the two groups. The hand, but not the wrist, index was found to correlate with the BMI. These results provide some support for a causative association between wrist morphometry, as measured by the wrist index, and CTS, but this difference is too small to be of diagnostic value in clinical or epidemiological practice. The results could also suggest that the previously reported association between CTS and the hand index may be secondary to differences in the BMI.

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Surface replicas of normal and vitrified leaves of Datura insignis, Barb Rodr

Vitrification is a morphological and physiological disorder affecting plants during their in vitro vegetative propagation. Vitrified plants have a poor survival rate when transferred from in vitro to greenhouse conditions, a fact mainly due to water loss and dissecation. It has been shown that normal and vitreous leaves of Datura insignis differ in the frequency of normal and abnormal stomata. The purpose of this work was to compare the surface of normal and vitreous leaves of D. insignis, using a modification of the platinum/carbon replica method. Adaxial and abaxial leaf surfaces of normal plantlets have a smooth and homogenous cuticle. A granular aspect, probably due to leaf age, rarely occurs at the periphery of the epidermal cells. Both adaxial and abaxial leaf surfaces of vitrified plantlets show discontinuities in the cuticle, occurring at several regions of the outer periclinal cell walls. However, such discontinuities are most noticeable in the region between adjacent epidermal cells. Fibrils 20–30 nm thick show a random arrangement or an oriented pattern in cuticular discontinuities. In D. insignis vitrified plantlets, adaxial and abaxial leaf cuticle has discontinuities or gaps which may cause an increase in cuticular transpiration contributing to the low survival rate of vitrified plantlets.

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