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Comparison of Zones 1 to 4 Flexor Tendon Repairs Using Absorbable and Unabsorbable Four-strand Core Sutures




Absorbable sutures behave favourably in vitro and in an animal model. We report the outcome of flexor tendon injuries in a series of 272 consecutive patients treated over 45 months with a mean follow-up of 4 (range 3–12) months. Five hundred and seventy-six tendons were repaired in 416 digits. The patients were not randomised and all repairs were performed using a Strickland four-strand core technique. In 191 (73%) patients an absorbable core suture was used (Group 1) and in 81 (27%) a non-absorbable material was used (Group 2). There were six ruptures (2%) in Group 1 and two (2%) in Group 2. Using the original Strickland criteria, there were 72% excellent/good and 28% fair/poor results in the absorbable core suture group, and 73% and 27%, respectively, in the non-absorbable core suture group. This study suggests that appropriate absorbable core sutures can be used safely for flexor tendon repair.




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Quantitative Energy Dispersive X-ray Microanalysis of Electron Beam-Sensitive Alloyed Nanoparticles
Research Articles
Nadi Braidy, Zygmunt J. Jakubek, Benoit Simard, Gianluigi A. Botton,
Microscopy and Microanalysis, Volume 14 Issue 02 , pp 166-175

Abstract
An energy dispersive X-ray spectrometry (EDXS) method is developed to evaluate the composition of alloyed nanoparticles (NPs) where one of the alloying elements is removed under the electron beam during microanalysis with a transmission electron microscope (TEM). The method is demonstrated for alloyed Au-Ag NPs of a diameter ranging from 6 to 20 nm produced by laser evaporation of a water-suspended Ag-Au powder mixture of varying composition. Series of EDXS spectra are recorded for 30 NPs from samples with five different Ag:Au ratios revealing Ag depletion from NPs during electron irradiation. By studying the evolution of NPs composition as a function of dose, the initial Ag content for each NP is extrapolated. The rate of Ag depletion is discussed in terms of sputtering and knock-on damage. On average, approximately one Ag atom is lost from the NP for each Ag L X-ray detected. To assess the limitations of microanalysis in these sensitive nanoscale structures, the concept of detectability limit is adapted to our method. This benchmark is then evaluated for Ag in Au-Ag NPs of various sizes and acquisition times. This study should be regarded as a guide for the design of analytical TEM measurements of beam-sensitive NPs.
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Chromosomal Laboratories Appoints R. Vincent Miller, Ph.D., Vice President And Chief Technical Officer
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Follicular Lymphoma of the Duodenum: A Clinicopathologic Analysis of 26 Cases
Objective

Follicular lymphomas (FLs) occur commonly in the lymph nodes, and duodenal FL (DFL) is reported to be rare.

Methods

We analysed the clinical, morphological, immunohistochemical and genetic features of 26 cases of DFL. Primary DFLs and systemic FLs that involved the duodenum at any point during the clinical course were included in the analysis.

Results

Typically, primary DFLs (14 cases) were found incidentally at routine medical check-ups, whereas involvement of the duodenum by systemic FLs (12 cases) was found through staging procedures. All cases involved the second portion of the duodenum. Helicobacter pylori infection was common (71%). In all cases, the histologic grade was low (either grade 1 or 2), and CD20, CD10 and Bcl-2 were positive by immunohistochemistry. Immunoglobulin heavy chain gene (IGH) and bcl-2 gene (BCL2) fusion was frequently shown by fluorescence in situ hybridization (FISH) analysis: nine of 12 cases (75%) of primary DFL and 10 of 12 cases (83%) of systemic DFL were positive. Treatment regimens employed were rituximab (R) plus chemotherapy (10), R (6), chemotherapy (3), irradiation (3) and the other three patients were subjected to observation. After a median follow-up duration of 40 months (ranging 11–96 months), 17 patients were alive without disease, seven were alive with disease and one had died of lymphoma.

Conclusions

Primary DFLs resemble systemic and nodal FLs, except that the former has high incidence of early stage and low-grade histology. The duodenum appears to be a frequently involved extranodal site of FL with IGH/BCL2.

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New Quantum State of Matter?
In a Nature article published yesterday, Princeton University scientists have shown that the Quantum Hall Effect can occur in nature in a way that wasn't predicted - they've recorded the behavior of electrons in a bulk crystal of bismuth-antimony without any external magnetic field being present. The fundamental research could also lead to advances in new kinds of fast quantum or "spintronic" computing devices.

The Quantum Hall Effect has only been seen previously in atomically thin layers of semiconductors in the presence of a very high applied magnetic field.

See Science Daily.
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Summer Invention Camp
Here is some good press for "Camp Invention." These are week-long camps using materials provided by the National Inventors Hall of Fame. According to the article, they are reaching about 60,000 kids in 47 states.

Camp Invention has a sister program, Club Invention, that is designed for use in after-school programs during the regular school year. Here is a review of that program in the Consumer's Guide to Afterschool Science Resources.
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Preparation of TEM samples of ferritic alloys

We describe techniques for electropolishing irradiated ferritic specimens for examination under the TEM in situations where the foil quality is of utmost importance. First, we describe some modifications to the standard technique for making plan-view specimens aimed at optimizing the foil quality. Second, we describe a technique for making plan-view specimens from a region of buried damage in a specimen irradiated with 2 MeV Fe+ ions.

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Journal of Hand Surgery (European Volume)
By noreply@blogger.com (Jason) - version: v1.5 build A